报告题目:Uterine Luminal/Epithelial LPA3 and Progesterone Receptor in Embryo Implantation
报告人: Xiaoqin Ye, M.D, Ph.D.
Assistant Professor, Department of Physiology & Pharmacology
The University of Georgia
主持人: 冯新华 教授
The University of Georgia
主持人: 冯新华 教授
时 间: 2011年6月3日(星期五)下午4点
地 点: 医学院综合楼205报告厅
Brief Introduction of Speaker:
Dr. Xiaoqin Ye received her M.D (1990) from Beijing Medical University (now Peking University), MPH (1993) from Chinese Academy of Preventive Medicine and Ph.D. (1999) University of California at Riverside. Dr. Ye’s research in her laboratory focuses on lysophospholipid signaling in reproduction and reproductive toxicology . Dr. Ye’s works have been published in Nature , Mol Cell Biol, JBC, Fertil Steril and Annu Rev Biochem etc.
Selected Publications:
1. Diao, H.L., Xiao, S., Zhao, F., and Ye, X. (2010). Uterine luminal epithelium specific proline-rich acidic protein 1 (PRAP1) as a marker for successful embryo implantation. Fertil Steril, 94:2808-2811 e2801.
2. Ye, X., and Chun, J. (2010). Lysophosphatidic acid (LPA) signaling in vertebrate reproduction. Trends Endocrinol Metab, 21:17-24.
3. Ye, X. (2008). Lysophospholipid signaling in the function and pathology of the reproductive system. Hum Reprod Update, 14:519-536.
4. Ye, X., Skinner, M.K., Kennedy, G., and Chun, J. (2008). Age-dependent loss of sperm production in mice via impaired lysophosphatidic acid signaling. Biol Reprod, 79:328-336.
5. Ye, X.*, Hama, K.*, Contos, J.J., Anliker, B., Inoue, A., Skinner, M.K., Suzuki, H., Amano, T., Kennedy, G., Arai, H., et al. (2005). LPA3-mediated lysophosphatidic acid signalling in embryo implantation and spacing. Nature, 435:104-108. (Comment in: Nature. 2005 May 5; 435(7038): 34-5.) "*equal authorship"
6. Ishii, I., Fukushima, N., Ye, X., and Chun, J. (2004). Lysophospholipid receptors: signaling and biology. Annu Rev Biochem, 73:321-354.
7. Ye, X., Fukushima, N., Kingsbury, M.A., and Chun, J. (2002). Lysophosphatidic acid in neural signaling. Neuroreport, 13:2169-2175.
8. Contos, J.J., Ishii, I., Fukushima, N., Kingsbury, M.A., Ye, X., Kawamura, S., Brown, J.H., and Chun, J. (2002). Characterization of lpa(2) (Edg4) and lpa(1)/lpa(2) (Edg2/Edg4) lysophosphatidic acid receptor knockout mice: signaling deficits without obvious phenotypic abnormality attributable to lpa(2). Mol Cell Biol, 22:6921-6929.
9. Ishii, I., Ye, X., Friedman, B., Kawamura, S., Contos, J.J., Kingsbury, M.A., Yang, A.H., Zhang, G., Brown, J.H., and Chun, J. (2002). Marked perinatal lethality and cellular signaling deficits in mice null for the two sphingosine 1-phosphate (S1P) receptors, S1P(2)/LP(B2)/EDG-5 and S1P(3)/LP(B3)/EDG-3. J Biol Chem, 277:25152-25159.