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2011.9.9 朱永群博士(美国Sloan-Kettering研究所)学术报告

时间:2011年09月08日 访问次数:1059

报告题目: Structural Insights into the Interaction between Bacterial Pathogen and the Host Cell

报告人:    Yongqun Zhu, Ph.D.
                  Research Associate, Howard Hughes Medical Institute (HHMI)
                  Sloan-Kettering Institute, Memorial Sloan-Kettering Cancer Center

主持人:   冯新华 教授 

时   间:   201199日(星期五)下午3点  

地   点:   医学院综合楼205报告厅
  
Selected Papers:

 

1.      Yongqun Zhu, Hongtao Li,Chengzu Long, Liyan Hu, Hao Xu, Liping Liu, She Chen,Da-Cheng Wang, and Feng Shao. Structural Insights into the Enzymatic Mechanism of the Pathogenic MAPK Phosphothreonine Lyase. Molecular Cell. 28, 899–913, Dec 14, 2007.

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

 

8.      Yong-Qun Zhu, De-Yu Zhu, Hong-Xia Lu, Na Yang, Gen-Pei Li, Da-Cheng Wang. Purification and Preliminary Crystallographic Studies of CutC, a Novel Copper Homeostasis Protein from Shigella flexneri. Protein & Peptide Letters. 12, 823-826, 2005.

 

7.      De-Yu Zhu, Yong-Qun Zhu*, Ye Xiang and Da-Cheng Wang. Optimizing Protein Crystal Growth through Dynamic Seeding. Acta Cryst. (2005). D61, 772-775. (*equal contribution)

 

6.      De-Yu Zhu, Yong-Qun Zhu*, Ren-Huai Huang, Ye Xiang, Na Yang, Hong-Xia Lu, Gen-Pei Li, Qi Jin, and Da-Cheng Wang. Crystal Structure of the Copper Homeostasis Protein (CutCm) from Shigella flexneri at 1.7Å Resolution: The First Structure of a New Sequence Family of TIM Barrels. PROTEINS.58:764–768, 2005. (* equal contribution)

 

5.      Yong-Qun Zhu, De-Yu Zhu, Lei Yin, Ying Zhang, Clemens Vonrhein, and Da-Cheng Wang. Crystal Structure of Human Spermidine/Spermine N1-Acetyltransferase (hSSAT): The First Structure of a New Sequence Family of Transferase Homologous Superfamily. PROTEINS. 63:1127–1131, 2006.

 

4.      Qing Yao, Jixin Cui, Yongqun Zhu, Guolun Wang, Liyan Hu, Chengzu Long, Ran Cao, Xinqi Liu, Niu Huang, She Chen, Liping Liu, and Feng Shao.  A bacterial type III effector family uses the papain-like hydrolytic activity to arrest the host cell cycle. Proc Natl Acad Sci USA. 2009 Mar 10; 106(10):3716-21.  

 

3.      Yongqun Zhu, Liyan Hu, Yan Zhou, Qing Yao, and Feng Shao. Structural mechanism of host Rab1 activation by the bifunctional Legionella type IV effector SidM/DrrA. Proc Natl Acad Sci USA. 2010 Mar 9; 107(10):4699-704.

 

2.      Yongqun Zhu, Hongtao Li, Jiayi Wang, Liyan Hu, Yan Zhou, Liping Liu, Feng Shao.  Structure of a Shigella effector reveals a new class of ubiquitin ligases. Nature  Structural & Molecular Biology. 15(12):1302-8, Dec 2008.

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