PUBLICATIONS

Peer-Reviewed Original Research Articles

1.     Li, L, Guo, W, Wang, J, Li, Z, Zhang, N. Chemical synthesis and secretive expression of a human ANF gene in E. coli. Chinese Biochemical Journal 7:487-91, 1991.

2.     Li, L, Li, G, Wang, J, Zhang, N, Tong, J, Li, Z. Site-specific mutagenesis of the hANF gene and its secretive expression. Chinese Biochemical Journal 7:492-5, 1991.

3.     Li L, Bales ES, Peterson CA, Legerski RJ. Characterization of molecular defects in xeroderma pigmentosum group C. Nat Genet 5(4):413-7, 12/1993. PMID: 8298653.

4.     Legerski RJ, Liu P, Li L, Peterson CA, Zhao Y, Leach RJ, Naylor SL, Siciliano MJ. Assignment of xeroderma pigmentosum group C (XPC) gene to chromosome 3p25. Genomics 21(1):266-9, 5/1994. PMID: 8088800.

5.     Li L, Elledge SJ, Peterson CA, Bales ES, Legerski RJ. Specific association between the human DNA repair proteins XPA and ERCC1. Proc Natl Acad Sci U S A 91(11):5012-6, 5/1994. PMCID: PMC43920.

6.     Li L, Peterson CA, Lu X, Legerski RJ. Mutations in XPA that prevent association with ERCC1 are defective in nucleotide excision repair. Mol Cell Biol 15(4):1993-8, 4/1995. PMCID: PMC230426.

7.     Henning KA, Li L, Iyer N, McDaniel LD, Reagan MS, Legerski R, Schultz RA, Stefanini M, Lehmann AR, Mayne LV, Friedberg EC. The Cockayne syndrome group A gene encodes a WD repeat protein that interacts with CSB protein and a subunit of RNA polymerase II TFIIH. Cell 82(4):555-64, 8/1995. PMID: 7664335.

8.     Pan ZQ, Reardon JT, Li L, Flores-Rozas H, Legerski R, Sancar A, Hurwitz J. Inhibition of nucleotide excision repair by the cyclin-dependent kinase inhibitor p21. J Biol Chem 270(37):22008-16, 9/1995. PMID: 7665622.

9.     Li L, Lu X, Peterson CA, Legerski RJ. An interaction between the DNA repair factor XPA and replication protein A appears essential for nucleotide excision repair. Mol Cell Biol 15(10):5396-402, 10/1995. PMCID: PMC230789.

10.  Li L, Peterson C, Legerski R. Sequence of the mouse XPC cDNA and genomic structure of the human XPC gene. Nucleic Acids Res 24(6):1026-8, 3/1996. PMCID: PMC145764.

11.  Li L, Lu X, Peterson C, Legerski R. XPC interacts with both HHR23B and HHR23A in vivo. Mutat Res 383(3):197-203, 5/1997. PMID: 9164480.

12.      Wei Q, Guan Y, Cheng L, Radinsky R, Bar-Eli M, Tsan R, Li L, Legerski RJ. Expression of five selected human mismatch repair genes simultaneously detected in normal and cancer cell lines by a nonradioactive multiplex reverse transcription-polymerase chain reaction. Pathobiology 65(6):293-300, 1997. PMID: 9491849.

13.  Khan SG, Levy HL, Legerski R, Quackenbush E, Reardon JT, Emmert S, Sancar A, Li L, Schneider TD, Cleaver JE, Kraemer KH. Xeroderma pigmentosum group C splice mutation associated with autism and hypoglycinemia. J Invest Dermatol 111(5):791-6, 11/1998. PMID: 9804340.

14.  Marathi UK, Dahlen M, Sunnerhagen P, Romero AV, Ramagli LS, Siciliano MJ, Li L, Legerski RJ. RAD1, a human structural homolog of the Schizosaccharomyces pombe RAD1 cell cycle checkpoint gene. Genomics 54(2):344-7, 12/1998. PMID: 9828139.

15.  Li L, Peterson CA, Kanter-Smoler G, Wei YF, Ramagli LS, Sunnerhagen P, Siciliano MJ, Legerski RJ. hRAD17, a structural homolog of the Schizosaccharomyces pombe RAD17 cell cycle checkpoint gene, stimulates p53 accumulation. Oncogene 18(9):1689-99, 3/1999. PMID: 10208430.

16.  Li L, Peterson CA, Lu X, Wei P, Legerski RJ. Interstrand cross-links induce DNA synthesis in damaged and undamaged plasmids in mammalian cell extracts. Mol Cell Biol 19(8):5619-30, 8/1999. PMCID: PMC84414.

17.  Cheng L, Guan Y, Li L, Legerski RJ, Einspahr J, Bangert J, Alberts DS, Wei Q. Expression in normal human tissues of five nucleotide excision repair genes measured simultaneously by multiplex reverse transcription-polymerase chain reaction. Cancer Epidemiol Biomarkers Prev 8(9):801-7, 9/1999. PMID: 10498399.

18.  Sturgis EM, Castillo EJ, Li L, Zheng R, Eicher SA, Clayman GL, Strom SS, Spitz MR, Wei Q. Polymorphisms of DNA repair gene XRCC1 in squamous cell carcinoma of the head and neck. Carcinogenesis 20(11):2125-9, 11/1999. PMID: 10545415.

19.  Li L and Liao WS. An upstream repressor element that contributes to hepatocyte-specific expression of the rat serum amyloid A1 gene. Biochemical & Biophysical Research Communications 264:2125-2129, 1999. PMID: 10529375.

20.  Li L, Peterson CA, Zhang X, Legerski RJ. Requirement for PCNA and RPA in interstrand crosslink-induced DNA synthesis. Nucleic Acids Res 28(6):1424-7, 3/2000. PMCID: PMC111036.

21.  Zhang N, Zhang X, Peterson C, Li L, Legerski R. Differential processing of UV mimetic and interstrand crosslink damage by XPF cell extracts. Nucleic Acids Res 28(23):4800-4, 12/2000. PMCID: PMC115165.

22.  Sturgis EM, Zheng R, Li L, Castillo EJ, Eicher SA, Chen M, Strom SS, Spitz MR, Wei Q. XPD/ERCC2 polymorphisms and risk of head and neck cancer: a case-control analysis. Carcinogenesis 21(12):2219-23, 12/2000. PMID: 11133811.

23.  Wang X, Peterson CA, Zheng H, Nairn RS, Legerski RJ, Li L. Involvement of nucleotide excision repair in a recombination-independent and error-prone pathway of DNA interstrand cross-link repair. Mol Cell Biol 21(3):713-20, 2/2001. PMID: 11154259.

24.  Li L, Story M, Legerski RJ. Cellular responses to ionizing radiation damage. Int J Radiat Oncol Biol Phys 49(4):1157-62, 3/2001. PMID: 11240259.

25.  Zheng Y, Li L, Shen H, Sturgis EM, Eicher SA, Strom SS, Spitz MR, Wei Q. Polymorphic hCHK2/hCds1 codon 84 allele and risk of squamous cell carcinoma of the head and neck--a case-control analysis. Carcinogenesis 22(12):2005-8, 12/2001. PMID: 11751432.

26.  Wang, X, Wang, L, McAllester, MD, Putnam, JB, M, Mao, L, Li, L. hRad17 is phosphorylated in response to DNA damage and also overexpressed in human non-small cell lung cancer tissues. Cancer Research advances in brief. 61:7417-21, 2001.

27.  Sturgis EM, Castillo EJ, Li L, Eicher SA, Strom SS, Spitz MR, Wei Q. XPD/ERCC2 EXON 8 Polymorphisms: rarity and lack of significance in risk of squamous cell carcinoma of the head and neck. Oral Oncol 38(5):475-7, 7/2002. PMID: 12110342.

28.  Vasques, KM, Christensen, J, Li, L, Finch, RA, Glazer, PM. Human XPA and RPA DNA repair proteins participate in specific recognition of triplex-induced helical distortions. Proc Natl Acad Sci U S A 99:5848-53, 2002. PMCID: PMC122865.

29.  Wang, X, Zou, Lee, Zheng, H, Wei, Q, Elledge, SJ, Li, L. Genomic Instability and Endoreduplication Triggered by RAD17 Deletion. Genes & Development 17:965-970, 2003.

30.  Zheng H, Wang X, Warren AJ, Legerski RJ, Nairn RS, Hamilton JW, Li L. Nucleotide excision repair- and polymerase eta-mediated error-prone removal of mitomycin C interstrand cross-links. Mol Cell Biol 23(2):754-61, 2003. PMCID: PMC151552.

31.  Wang W, Yang Y, Li L, Shi Y. Synleurin, a novel leucine-rich repeat protein that increases the intensity of pleiotropic cytokine responses. Biochemical and Biophysical Research Communication 305:981-988, 2003.

32.  Bao, S, Wang, X, Huyong Zheng, Lu, T, Hittleman W, Li, L. Disruption of the Rad9/Rad1/Hus1 (9-1-1) Complex Leads to Checkpoint Signaling and Replication Defects. Oncogene 23:5586-5593, 2004.

33.  Zhang N, Kaur R, Lu X, Shen X, Li L, Legerski RJ. The Pso4 mRNA splicing and DNA repair complex interacts with WRN for processing of DNA interstrand cross-links. J Biol Chem 280(49):40559-67, 12/2005. PMID: 16223718.

34.  Yin, J, Sobeck, A, Xu, C, Meetei, AR, Hoatlin, M, Li, L, Wang, W. BLAP75, an Essential Component of Bloom Syndrome Protein Complexes that Maintain Genome Integrity. EMBO Journal 24:1465-1476, 2005. PMCID: PMC1152546.

35.  Wang X, Zou L, Lu T, Bao S, Hurov KE, Hittelman WN, Elledge SJ, Li L. Rad17 phosphorylation is required for claspin recruitment and Chk1 activation in response to replication stress. Mol Cell 23:331-41, 8/2006. PMID: 16885023.

36.  Park JI, Ji H, Jun S, Gu D, Hikasa H, Li L, Sokol SY, McCrea PD. Frodo links Dishevelled to the p120-catenin/Kaiso pathway: distinct catenin subfamilies promote Wnt signals. Dev Cell 11:683-95, 11/2006. PMID: 17084360.

37.  Wu, L, Ou, J, Xu, C, Yin, J, Chang, M, Wang, W, Li, L, Brown, GW, Hickson, I. BLAP75/RMI1 promotes the BLM-dependent dissolution of homologous recombination intermediates. Proc Natl Acad Sci U S A 103:4068-4073, 2006. PMCID: PMC1449647.

38.  Zhen, HY, Wang, X, Legerski, RJ, Glazer, PM, Li, L. Repair of DNA Interstrand cross-links: Interactions between homology-dependent and homology-independent pathways. DNA Repair 5:566-574, 2006.

39.  Shen, X, Jun, S, O'Neal, LE, Sonod, E, Bemark, M, Sale, E, Li, L. REV3 and REV1 play major roles in recombination-independent repair of DNA interstrand cross-links mediated by monoubiquitinated proliferating cell nuclear antigen (PCNA). J Biol Chem 281:13869-13872, 2006.

40.  Zhang N, Liu X, Li L, Legerski R. Double-strand breaks induce homologous recombinational repair of interstrand cross-links via cooperation of MSH2, ERCC1-XPF, REV3, and the Fanconi anemia pathway. DNA Repair (Amst) 6(11):1670-1678, 11/2007. e-Pub 7/2007. PMCID: PMC2586762.

41.  Bae JB, Mukhopadhyay SS, Liu L, Zhang N, Tan J, Akhter S, Liu X, Shen X, Li L, Legerski RJ. Snm1B/Apollo mediates replication fork collapse and S Phase checkpoint activation in response to DNA interstrand cross-links. Oncogene 27(37):5045-5056, 8/2008. e-Pub 5/2008. PMCID: PMC2805112.

42.  Shen X, Do H, Li Y, Chung W-H, Tomasz M, deWinter JP, Xia B, Elledge SJ Wang W, Li L. Recruitment of Fanconi anemia and breast cancer proteins to DNA damage sites is differentially governed by replication. Mol Cell 35(5):716-23, 9/2009. PMCID: PMC2758766.

43.  Bu W, Xin L, Toneff M, Li L, Li Y. Lentivirus vectors for stably introducing genes into mammary epithelial cells in vivo. J Mammary Gland Biol Neoplasia 14(4):401-4, 12/2009. e-Pub 11/2009. PMID: 19936990.

44.  Yan Z, Delannoy M, Ling C, Daee D, Osman F, Muniandy PA, Shen X, Oostra AB, Du H, Steltenpool J, Lin T, Schuster B, Décaillet C, Stasiak A, Stasiak AZ, Stone S, Hoatlin ME, Schindler D, Woodcock CL, Joenje H, Sen R, de Winter JP, Li L, Seidman MM, Whitby MC, Myung K, Constantinou A, Wang W. A histone-fold complex and FANCM form a conserved DNA-remodeling complex to maintain genome stability. Mol Cell 37(6):865-78, 3/2010. PMCID: PMC2847587.

45.  Shen X, Li L. Mutagenic Repair of DNA Interstrand Crosslinks. Environ Mol Mutagen 51(6):493-9, 7/2010. e-Pub 3/2010. PMCID: PMC2892553.

46.  Zhou Z, Sun X, Zou Z, Sun L, Zhang T, Guo S, Wen Y, Liu L, Wang Y, Qin J, Li L, Gong W, Bao S. PRMT5 regulates Golgi apparatus structure through methylation of the golgin GM130. Cell Research 20:1023, , 9/2010. e-Pub 4/2010.

47.  Xu D, Muniandy P, Leo E, Yin J, Thangavel S, Shen X, Ii M, Agama K, Guo R, Fox D, Meetei AR, Wilson L, Nguyen H, Weng NP, Brill SJ, Li L, Vindigni A, Pommier Y, Seidman M, Wang W. Rif1 provides a new DNA-binding interface for the Bloom syndrome complex to maintain normal replication. EMBO J 29(18):3140-55, 9/2010. e-Pub 8/2010. PMCID: PMC2944062.

48.  Jiang Y, Wang X, Bao S, Guo R, Johnson DG, Shen X, Li L. INO80 chromatin remodeling complex promotes the removal of UV lesions by the nucleotide excision repair pathway. Proc Natl Acad Sci U S A 107(40):17274-9, 10/2010. e-Pub 9/2010. PMCID: PMC2951448.

49.  Chen H, You MJ, Jiang Y, Wang W, Li L. RMI1 Attenuates tumor development and is essential for early embryonic survival. Mol Carcinog 99(6). e-Pub 11/2010. PMID: 21104988.

50.  Zhijiang Y, Guo R, Paramasivam M, Shen W, Fox D, Ling C, Wang Y, Oostra A, Kuehl J, Duck-Yeon L, Takata M, Hoatlin M, Schindler D, Joenje H, de Winter J, Li L, Seidman M, Wang W. A novel ubiquitin-binding protein links RNF8-mediated ubiquitination to the Fanconi anemia DNA Repair network. Molecular Cell 47(1):61-75, 3/2012. PMCID: PMC3398238.

51.  Leung JW, Wang Y, Fong KW, Huen MS, Li L, Chen J. Fanconi anemia (FA) binding protein FAAP20 stabilizes FA complementation group A (FANCA) and participates in interstrand cross-link repair. Proc Natl Acad Sci U S A. 109(12):4491-4496, http://www.pnas.org/content/109/12/4491.long, 3/2012. PMCID: PMC3311328.

52.  Leung JW, Ghosal G, Wang W, Shen X, Wang J, Li L, Chen J. Alpha thalassemia/mental retardation syndrome X-linked gene product ATRX is required for proper replication restart and cellular resistance to replication stress. J Biol Chem 288(9):6342-50, 3/2013. e-Pub 1/2013. PMCID: PMC3585069.

53.  Wang Y, Leung JW, Jiang Y, Lowery MG, Do H, Vasquez KM, Chen J, Wang W, Li L. FANCM and FAAP24 maintain genome stability via cooperative as well as unique functions. Mol Cell 49(5):997-1009, 3/2013. e-Pub 1/2013. PMCID: PMC3595374.

54.  Wang ML, Rule S, Martin P, Goy A, Auer R, Kahl BS, Jurczak W, Advani RH, Romaguera JE,  Williams ME, Barrientos JC, Chmielowska E, Radford J,  Stilgenbauer S, Dreyling M, Wieslaw WJ, Johnson P, Spurgeon SE, Li L, Zhang L, Newberry K, Ou Z, Cheng N, Fang B, McGreivy J,  Clow F, Buggy J, Chang B, Beaupre D, Kunkel L, Blum K. Targeting Bruton’s Tyrosine Kinase with Ibrutinib in Relapsed/Refractory Mantle Cell Lymphoma. New England Journal of Medicine 369:507-516, 8/2013. e-Pub 6/2013.

55.  Chandan Shee, Ben D Cox, Franklin Gua, Elizabeth M Luengas, Mohan C Joshi, David Magnan, Jennifer A. Halliday, Ryan L Frisch, Ralf Bernd Nehring, Huong G Do, Marcos Hernandez, Li L, Christophe Herman, PJ Hastings, David Bates, Reuben S Harris, Kyle M Miller, Susan M Rosenberg. Engineered proteins detect spontaneous DNA breakage in human and bacterial cells. eLIFE 2:e01222, 10/2013.

56.  Wang Y, Han X, Wu F, Leung JW, Lowery MG, Do H, Chen J, Shi C, Tian C, Li L, Gong W. Structure Analysis of FAAP24 Reveals Single Stranded DNA Binding Activity and Domain Functions in DNA Damage Response. Cell Res 23(10):1215-1228, http://dx.doi.org/10.1038/cr.2013.124, 10/2013. e-Pub 9/2013. PMCID: PMC3790240.

57.  Jin-Na Min, Yanyan Tian, Yang Xiao, Ling Wu, Li Li, Sandy Chang. The mINO80 chromatin remodeling complex is required for efficient telomere replication and maintenance of genome stability. Cell Research 23(12):1396-1413, 12/2013. e-Pub 8/2013.

58.  Yaling Huang, Justin WC Leung, Megan Lowery, Nobuko Matsushita, Yucai Wang, Xi Shen, Do Huong, Minoru Takata4, Junjie Chen, Li L. Modularized Functions of the Fanconi Anemia Core Complex. Cell Report 7:1-9, 4/2014.

59.  Andy Castillo, Atanu Paul, Baohua Sun, Ting Hsiang Huang, Yucai Wang, Stephanie A. Yazinski, Jessica Tyler, Li L, M James You, Lee Zou, Jun Yao and Bin Wang. The BRCA1-interacting protein, Abraxas, is required for genomic stability and tumor suppression. Cell Report 8(3):807, 7/2014.

60.  Smith S, Fox J, Mejia M, Ruangpradit W, Saberi A, Kim S, Choi Y, Oh S, Wang Y, Choi K, Li L, Hendrickson EA, Takeda S, Muller M, Myung K. Histone deacetylase inhibitors selectively target homology dependent DNA repair defective cells and elevate non-homologous endjoining activity. PLoS One 9(1):e87203, 2014.

61.  Tian Y, Paramasivam M, Ghosal G, Chen D, Shen X, Huang Y, Akhter S, Legerski R, Chen J, Seidman MM, Qin J, Li L. UHRF1 Contributes to DNA Damage Repair as a Lesion Recognition Factor and Nuclease Scaffold. Cell Report, 10(12):1957-66, 3/2015. e-Pub 3/2015. PMID: 25818288.

62.  Phan L, Chou P, Velazquez-Torres G, Samudio I, Parreno K, Huang Y, Tseng T, .. Li L , Wei Yang, Lajos Pusztai, Sai-Ching Yeung, and Lee M-H. The cell cycle regulator 14-3-3σ opposes and reverses cancer metabolic reprogramming. Nature Comm., 6:7530, 7/2015.

63.  JunS,JungYS,SuhHN,WangW,KimMJ,OhYS,LienEM,ShenX,MatsumotoY,McCrea PD, Li L, Chen J, Park JI. LIG4 mediates Wnt signalling-induced radioresistance. Nat Commun7:10994,3/2016.e-Pub3/2016.PMCID:PMC4820809.

64.  WolfeAR,BambhroliyaA,ReddyJP,DebebBG,HuoL,LarsonR,LiL,UenoNT,Woodward WA. MiR-33a Decreases High-Density Lipoprotein-lnduced Radiation Sensitivity in Breast Cancer. Int J Radiat Oneal Biol Phys 95(2):791-9, 6/2016. e-Pub 1/2016. PMCID: PMC4851902.

65.  Debeb BG, Lacerda L, Anfossi S, Diagaradjane P, Chu K, Bambhroliya A, Huo L, Wei C, Larson RA, Wolfe AR, Xu W, Smith DL, Li L, Ivan C, Allen PK, Wu W, Calin GA, KrishnamurthyS,ZhangXH,BuchholzTA,UenoNT,ReubenJM,WoodwardWA.miR-141- Mediated Regulation of Brain Metastasis From Breast Cancer. J Natl Cancer Inst 108(8), 8/2016.e-Pub4/2016.PMCID:PMC5017951.

66.  Xia J, Chen LT, Mei Q, Ma CH, Halliday JA, Lin HY, Magnan D, Pribis JP, Fitzgerald DM, Hamilton HM, Richters M, Nehring RB, Shen X, Li L, Bates D, Hastings PJ, Herman C, JayaramM,RosenbergSM.Hollidayjunctiontrapshowshowcellsuserecombinationanda junction-guardian role of RecQ helicase. Sci Adv 2(11):e1601605, 11/2016. e-Pub 11/2016. PMCID:  PMC5222578.

67.  Chen J, Shukla V, Farci P, Andricovich J, Jogunoori W, Kwong LN, Katz LH, Shetty K, Rashid A, Su X, White J, Li L, Wang AY, Blechacz B, Raju GS, Davila M, Nguyen BN, StroehleinJR,ChenJ,KimSS,LevinH,MachidaK,TsukamotoH,MichaelyP,TzatsosA, MishraB,AmdurR,MishraL.Lossofthetransforminggrowthfactor-13effector132-Spectrin promotes genomic instability. Hepatology 65(2):678-693, 2/2017. e-Pub 12/2016. PMCID: PMC5432427.

68.  Zhang L, Nomie K, Zhang H, Bell T, Pham LV, Kadri S, Segal J, Li S, Zhou S, Santos D, Richard S, Sharma S, Chen W, Oriabure 0, Liu Y, Huang S, Guo H, Chen Z, Tao W, Li C, WangJ, FangB,WangJ,LiL,BadilloM,AhmedM,ThirumurthiS,HuangSY,ShaoY,Lam L, Yi Q, Wang L, Wang M. B-cell lymphoma patient-derived xenograft models enable drug discovery and are a platform for personalized therapy. Clin Cancer Res. e-Pub 3/2017. PMID:28348046.

69.  Tian Y, Shen Xi, Wang R, Klages-Mundt N, Lynn JE, Martin S., Ye Y, Gao M, Chen J, Schlacher K, and Li L. Constitutive role of the Fanconi anemia D2 gene in the replication stress response. J Biol Chem. 2017 Dec 8; 292(49): 20184–20195. doi: 10.1074/jbc.M117.814780.

70.  Wang H, Li S, Oaks J, Ren J, Li L, Wu X. The concerted roles of FANCM and Rad52 in the protection of common fragile sites. Nat Commun. 2018 Jul 18;9(1):2791. doi: 10.1038/s41467-018-05066-y. PMID: 30022024

71.  Knijnenburg TA, Wang L, Zimmermann MT, Chambwe N, Gao GF, Cherniack AD, Fan H, Shen H, Way GP, Greene CS, Liu Y, Akbani R, Feng B, Donehower LA, Miller C, Shen Y, Karimi M, Chen H, Kim P, Jia P, Shinbrot E, Zhang S, Liu J, Hu H, Bailey MH, Yau C, Wolf D, Zhao Z, Weinstein JN, Li L, Ding L, Mills GB, Laird PW, Wheeler DA, Shmulevich I; Cancer Genome Atlas Research Network, Monnat RJ Jr, Xiao Y, Wang C.Genomic and Molecular Landscape of DNA Damage Repair Deficiency across The Cancer Genome Atlas.Cell Rep. 2018 Apr 3;23(1):239-254. PMCID: PMC5961503

72.  Kotlajich MV, Xia J, Zhai Y, Lin HY, Bradley CC, Shen X, Mei Q, Wang AZ, Lynn EJ, Shee C, Chen LT, Li L, Miller KM, Herman C, Hastings PJ, Rosenberg SM. Fluorescent fusions of the N protein of phage Mu label DNA damage in living cells. DNA Repair (Amst). 2018 Dec;72:86-92

73.  Yan X, Zhang X, Wang L, Zhang R, Pu X, Wu S, Li L, Tong P, Wang J, Meng QH, Jensen VB, Girard L, Minna JD, Roth JA, Swisher SG, Heymach JV, Fang B. Inhibition of Thioredoxin/Thioredoxin Reductase Induces Synthetic Lethality in Lung Cancers with Compromised Glutathione Homeostasis. Cancer Res. 2019 Jan 1;79(1):125-132. PMID: 30401714.

74.  Hu Q, Klages-Mundt N, Lynn E, Saha L, Zhang H, Srivastava M, Wang R, Shen X, Tian Y, Kim Hyeung, Ye Yin, Takeda S, Paull T, Chen J, Li L. A sensitive and fast assay for DNA-protein crosslinks in living cells. Cell Rep. 2020 Jan 28;30(4):1235-1245. PMID: 31995761

75.  Shen X, Wang R, Kim J, Hu Q, Chih-Chao Hsu, C-C, Yao J, Klages-Mundt N, Tian Y, Lynn E, Arun B, Takada S, Chen J, Jae-il Park J-I, Shi X, Brewer TF, Christopher J. Chang CJ, Jung, SY, Qin J, Andreeff M, Li L. A surge of DNA damage links transcriptional reprogramming and hematopoietic deficit in Fanconi anemia. Molecular Cell, Vol. 80, Dec. 17, 2020.

76.  Wang R, Lenoir, WF, Wang C, Su D, McLaughlin M, Hu Q, Shen X, Tian Y, Klages-Mundt N, Lynn E, Wood RD, Chen J, Hart T, Li L. DNA Polymerase iota Compensates for Fanconi Anemia Pathway Deficiency by Countering DNA Replication Stress. Proc. Natl. Acad. Sci. Jan., 2021, in press.

Invited Articles

1.     Legerski, RJ, Li, L. DNA Repair Capability and Human Disease. Cancer Bulletin 46:228-232, 1994.

2.     Li, L, Legerski, R, Story, M. DNA repair following ionizing radiation. International Journal of Radiation Oncology, Biology, Physics 49:1157-1162, 2001.

3.     Qin J, Li L. Molecular Anatomy of the Damage and Replication Checkpoint. Radiation Research 159:139-148, 2003.

4.     Li, L and Zou, L. Sensing, Signaling, and Responding to DNA Damage: Organization of the Checkpoint Pathways in Mammalian Cells. Journal of Cell Biology 94:298-306, 2005.

5.     Li L. BRCA1 forks over new roles in DNA-damage response - before and beyond the breaks. Molecular Cell, 44(2):235-51, 10/2011. PMCID: PMC22017867.

6.     Huang Y, Li L. DNA crosslinking damage and cancer - a tale of friend and foe. Transl Cancer Res 2(3):144-154, http://www.thetcr.org/article/view/1080/html, 6/2013. e-Pub 6/2013. PMCID: PMC3755464.

7.     ZouLee andLiL.The2015AlbertLaskerBasicMedicalResearchAward:Anexhilaratingjourney to the DNA damage checkpoint. Sci China Life Sci 59(1):103-5, 1/2016. e-Pub 12/2015. PMID:26668018.

8.     Ahmed M, Li L, Pinnix C, Dabaja B, Nomie K, Lam L, Wang M. ATM mutation and radiosensitivity:Anopportunityinthetherapyofmantlecelllymphoma. Crit RevOncol Hematol107:14-19,11/2016.e-Pub8/2016.PMID:27823642.

9.     Klages-Mundt NL, Li L. Formation and repair of DNA-protein crosslink damage. Sci China Life Sci. 2017 Oct;60(10):1065-1076. PMID: 29098631

10.  Li L.The multiple fronts of conquering cancer. Sci China Life Sci. 2017 Oct;60(10):1055-1057. PMID: 29119375